Computational Oncology: Exploring the origin of colon cancer

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My second first-author paper is out in Computational and Systems Oncology. In addition to the Kronecker model, we, researchers from Heidelberg and Leipzig, have developed a computational model for the biological processes occurring within single crypts, small entities of the colon, during early cancer development in Lynch syndrome. The computer simulations allow to unravel the otherwise invisible cancer formation process.

Together with my co-authors and the HITS Communication team, we have written a blog post and newsletter items about the main ideas and findings. Please have a look at HITS Blog and HITS Newsletter Issue 3, also for a video on the simulations.

The source code of the simulations developed within the Chaste framework can be accessed on GitHub, release v1.0.